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CAS 120511-73-1 Anti Estrogen Anastrozole Powder

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CAS 120511-73-1 Anti Estrogen Anastrozole Powder

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Large Image :  CAS 120511-73-1 Anti Estrogen Anastrozole Powder Get Best Price

Product Details:
Place of Origin: China
Brand Name: Keray
Certification: SGS,ISO9001
Model Number: Anastrozole
Payment & Shipping Terms:
Minimum Order Quantity: 10gram
Price: Negotiable
Packaging Details: discreet and safe foil bag or tin
Delivery Time: 24 hours upon receipt of payment
Payment Terms: Bank Transfer,BTC
Supply Ability: 3000Kg/Month
Detailed Product Description
Product Name: Anastrozole Package: Discreet Package
Grade: Pharmaceutical Grade Other Name: Arimidex
Shelf Life: 2 Years CAS: 120511-73-1
Assays: 99% Effect: Breast Carcinoma
High Light:

Anti Estrogen Anastrozole Powder

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CAS 120511-73-1 Anastrozole Powder

Anastrozole Anti Estrogen Steroids Raw Powder Arimidex CAS 120511-73-1

 

99% Purity Anti Estrogen Steroids Powder Anastrozole / Arimidex Raw Powder CAS 120511-73-1​

Anastrozole

 

 
 

CAS:120511-73-1

MF:C17H19N5

MW:293.37

Synonyms:ICI-D-1033;ARIMIDEX;1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4-TRIAZOLE;ANASTRAZOLE;ANASTROZOLE;tetramethyl-5-(1h-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile;ZD-1033;1,3-benzenediacetonitrile,alpha,alpha,alpha’,alpha’-tetramethyl-5-(1h-1,2,4-t

 
 
Properties
 

Melting point:81-82°C

storage temp. Store at RT

solubility DMSO: soluble40mg/mL

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Safety Information
 

Symbol(GHS)

 

 

 

 

Description


Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.

As an aromatase inhibitor, Arimidex's mechanism of action - blocking conversion of aromatizable steroids to estrogen - is in contrast to the mechanism of action of anti-estrogens such as clomiphene (Clomid) or tamoxifen (Nolvadex), which block estrogen receptors in some tissues, and activate estrogen receptors in others. During a cycle, if using Arimidex, there is generally no need to use Clomid as well, but (as mentioned in the section on Clomid) there may still be benefits to doing so.

Arimidex at 0.5 mg/day is usually sufficient for moderate dosages of testosterone and in some cases may be too much.

 

Specifications

Items Standard Results
Description White crystalline powder Complies
Identification IR
HPLC
Reactive
Conform with standard IR
Conform with standard HPLC
Conform
Solubility Freely soluble in methanol,
acetone,ethanol and tetrahydrofuran.
And very soluble in acetonitrile
Complies
Total Impurity max.0.5% 0.18%
Total Unspecified Impurity max. 0.2% 0.08%
Individual unspecified impurlty max. 0.1% 0.05%
Related compound B max. 0.2% 0.07%
Related compound C max. 0.2% 0.04%
Related compound D max. 0.1% 0.05%
Related compound E max. 0.1% 0.06%
Limit of cyclohexane max. 0.08% ND
Limit of ethylacetate max. 0.1% 0.07%
Melting point 81.0~84.0ºC 82.5~83.2ºC
Water max. 0.3% 0.21%
Residue on ignition max. 0.1% 0.07%
Heavy Metals max.0.001% Complies
Assay(HPLC) 98.0%~102.0% 99.8%
Storage Cool and dry
Conclusion It complies to USP32 .

 

 

How ARIMIDEX works?

ARIMIDEX lowers the amount of oestrogen in the body. The female sex hormones oestrogen and progesterone stimulate many breast cancers to grow. Lowering the level of oestrogen can stop or slow the growth of breast cancer cells.

ARIMIDEX blocks a process called aromatisation which changes sex hormones called androgens into oestrogen. This happens mainly in the fatty tissues, muscle and the skin and needs a particular enzyme called aromatase.

Mechanism of Action:

The growth of many cancers of the breast is stimulated or maintained by estrogens.
In postmenopausal women, estrogens are mainly derived from the action of the aromatase enzyme, which converts adrenal androgens (primarily androstenedione and testosterone) to estrone and estradiol. The suppression of estrogen biosynthesis in peripheral tissues and in the cancer tissue itself can therefore be achieved by specifically inhibiting the aromatase enzyme.

ARIMIDEX is a selective non-steroidal aromatase inhibitor. It significantly lowers serum estradiol concentrations and has no detectable effect on formation of adrenal corticosteroids or aldosterone.

Adjuvant Treatment:

ARIMIDEX is indicated for adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer.

First-Line Treatment:

ARIMIDEX is indicated for the first-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer.

Second-Line Treatment:

ARIMIDEX is indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy. Patients with ER-negative disease and patients who did not respond to previous tamoxifen therapy rarely responded to ARIMIDEX.

Dosage and direction:

Follow all instructions of your doctor about treatment and dosing schedule. Do not take more of this medication than it was administered to you. Take once daily.

Very discreet and exquisite packing methods to guarantee 100% custom pass rate(with more than 16 years experience).
All products are produced in Aseptic Laboratory under GMP conditions. Top quality is guaranteed.We have passed ISO9001 in 2008.

CAS 120511-73-1 Anti Estrogen Anastrozole Powder 0

 

How to make an order :

1. Name what your need ( which product , quantity )
2. Full payment would be done once we come to an agreement on all details .
3. Parcel would be shipped out upon receipt of payment .
4. Info about parcel would be offered ( Photo , tracking number )
5. Finally you would get the parcel in 3~7 days .

 

 

 

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