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SR9009 Prohormone SARMS 1379686-29-9 Research Raw Chemical For Fitness Nutrition
Product Name: SR9009
Cas No.: 1379686-29-9
Molucelar weight: 479.03524
Packing:foil bag or as required
SR9009 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates.
SR9009 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols.
Usage levels of 5% to 10% by weight are recommended.
SR9009 is a potent and specific synthetic REV-ERB. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice.
The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
Certificate Of Analysis:
|Specific Rotation||+39°~ +43°||+40.2°|
|Organic Volatile Impurities||Conform||Conform|
|Loss On Drying||≤0.50%||0.27%|
|Residue On Ignition||≤0.10%||0.015%|
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